Marty Yang, BS, PhD

My research aims to uncover how the developing human brain builds hundreds of cell types from a single genomic blueprint. Using stem cell-derived assembloids, I am investigating how neural progenitors integrate neuronal ... Read More

Coordinated movement relies on the nervous system constructing a real-time representation of the body in space and time, grounded in proprioceptive signals of force, position, and motion. The cervical spinal cord is the ... Read More

Alzheimer's disease (AD) is the leading cause of dementia, and while genetics is the second strongest risk factor after aging, how specific gene variants disrupt microglia, the brain's immune cells, to drive disease prog... Read More

Animals constantly arbitrate between exploring to find new resources and exploiting their finds. In vertebrates, hypothalamic circuits tune this balance by integrating, for example, hunger to reshape movement patterns. T... Read More

This research investigates the circuit mechanisms underlying contextual modulation in the visual cortex — specifically, how somatostatin (SST) interneurons sculpt neural representations by selectively suppressing respo... Read More

My research investigates how microglial TBK1 signaling orchestrates immunosuppressive crosstalk among microglia, astrocytes, and T cells in breast cancer brain metastases. By defining how TBK1 shapes the metastatic brain... Read More

Accumulating evidence suggests the interaction between the nervous and immune systems, yet the mechanisms by which CNS-resident cells and CNS-recruited cells influence each other remain poorly understood. We employ mouse... Read More