Dheeraj Roy, Ph.D.

The neurobiological mechanisms underlying cognitive impairments in psychiatric disorders are not well understood. This project will help uncover the role of thalamic circuits in learning and memory, enhance our knowledge... Read More

Breathing is essential for life, yet the neural mechanisms by which the body senses cues from the airways remain poorly understood. We combine physiology, mouse genetics and molecular neuroscience tools to investigate th... Read More

Synapses are communication points between neurons that are the fundamental processing units of the nervous system; synapses also exist between neurons and non-neuronal cells called oligodendrocyte precursor cells, but h... Read More

Exposing mouse models of Alzheimer’s Disease to sensory gamma stimulation (lights and sounds that flicker at 40 Hz) rescues both neural and cognitive functions, but few studies have examined how sensory gamma stimulati... Read More

Reinforcement learning is a fundamental learning process that is essential for cognitive flexibility, and deficits in the process underlie a number of symptoms in neurological and psychiatric disorders. This project will... Read More

Anti-NMDAR encephalitis (NMDARE) is an enigmatic autoimmune disease caused by antibodies targeting the GluN1 subunit of NMDARs and leads to long-term cognitive deficits in the majority of cases and can be fatal in some p... Read More

This project will investigate a group of diseases in which the patients accumulate a specific fat corresponding to Very long-chain fatty acids (VLCFA), leading to inflammatory responses in the nervous system. Research in... Read More